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Published on: November 12, 2021
Bromophycolides C-I from the Fijian red alga Callophycus serratus
Julia Kubanek1, Anne C Prusak, Terry W Snell
1School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, USA. julia.kubanek@biology.gatech.edu
Abstract:
Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.
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