Anthraquinone derivatives from Heterophyllaea pustulata
Susana C Núñez Montoya1, Alicia M Agnese, José L Cabrera
1Farmacognosia, Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, IMBIV-CONICET, 5000 Córdoba, Argentina.
Abstract:
From the leaves of Heterophyllaea pustulata two new monomeric anthraquinones, heterophylline (1,6-dihydroxy-7-methoxy-2-methylanthraquinone, 1) and pustuline (2-hydroxy-3-methoxy-7-methylanthraquinone, 2), and one new bianthraquinone, (S)-5,5'-bisoranjidiol [(S)-5,5'-bis(1,6-dihydroxy-2-methylanthraquinone), 3], were isolated. Furthermore, the iridoid glycoside asperuloside and three known flavonoids, quercetin, isoquercitrin, and quercetin-3-O-beta-d-glucosyl-6' '-acetate, were obtained. The structures were determined by analysis of their spectroscopic data and chemical evidence.
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