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Published on: August 31, 2018
Sarcophytonolides E-H, cembranolides from the Hainan soft coral Sarcophyton latum
Rui Jia1, Yue-Wei Guo, Ernesto Mollo
1State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institute for Biological Sciences, Shanghai 201203, People's Republic of China.
Abstract:
Four new cembrane diterpenes, sarcophytonolides E-H (1-4), were isolated from the Hainan soft coral Sarcophyton latum. Their structures were elucidated by detailed spectroscopic (IR, MS, 2D NMR) analysis and by comparison with related known compounds. The absolute stereochemistry of sarcophytonolide H (4) was determined by applying the modified Mosher's method.
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