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Improved method to induce superovulation in cattle using Human Menopausal Gonadotropin (HMG).
A Lauria1, O Oliva, A R Genazzani
1Istituto di Anatomia degli Animali Domestici con Istologia ed Embriologia dell 'Università di Milano Via Celoria, 10 - 20133 Milano - Italy.
Theriogenology
|September 1, 1982
Summary
This study optimized superovulation protocols for cattle using Pergonal 500, achieving excellent results in both heifers and cows for embryo transfer. The new treatment schedule yielded high numbers of transferable embryos and rapid cycle restoration.
Area of Science:
- Veterinary Medicine
- Reproductive Biology
- Animal Science
Background:
- Previous studies indicated favorable use of Human Menopausal Gonadotropin (HMG) for superovulation in heifers.
- Further clinical and endocrinological investigations were needed to refine treatment schedules.
Purpose of the Study:
- To evaluate a novel treatment schedule for inducing superovulation in Friesian heifers and lactating cows.
- To assess the efficacy of this protocol for embryo transfer practices.
Main Methods:
- Administered Pergonal 500 (HMG) at specific intervals to heifers and cows from day 9-11 of their cycle.
- Utilized Estrumate and Human Chorionic Gonadotropin (HCG) to synchronize estrus and ovulation.
- Monitored clinical and endocrinological responses, and collected transferable embryos.
Main Results:
- All animals responded positively to the superovulatory stimulus, with no donor yielding fewer than two transferable embryos.
- Achieved mean ovulation numbers of 11.66 in heifers and 10.36 in cows.
- Reported a 67% rate of transferable embryos and rapid restoration of estrous cycles.
Conclusions:
- The adopted treatment schedule effectively induced satisfactory superovulation in both heifers and cows.
- The protocol is suitable for embryo transfer practices, demonstrating high embryo yield and minimal follicular issues.
- The results support the optimized use of HMG-based protocols in cattle reproduction.