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Updated: Aug 8, 2026
Murine Prostate Micro-dissection and Surgical Castration
Published on: May 11, 2016
Effects of unilateral castration on morphologic characteristics of the testis in one-, two-, and three-year-old
T A Hoagland1, K M Ott, J E Dinger
1Department of Animal Science University of Connecticut, Storrs, CT 06268 USA; Department of Pathobiology University of Connecticut, Storrs, CT 06268 USA.
Abstract:
The effects of unilateral castration on testicular compensatory hypertrophy were measured in 12 Morgan stallions, four each at one, two, and three years of age. They were randomized within age to intact (IN) or unilaterally castrated (UC) groups. Allotment and surgery were in January 1983 and total castration was in June 1983, 150 d after unilateral castration. Testis weight increased linearly with age (P < 0.01) and was increased by unilateral castration (P < 0.07). Epididymal weight also increased linearly with age (P < 0.05) and was heavier in UC animals (P = 0.15). Tubule diameter (P < 0.10) and epithelial height (P < 0.03) were greater in UC than in IN stallions. In conclusion, testes of stallions underwent compensatory hypertrophy after unilateral castration.