Related Experiment Video
Updated: Aug 8, 2026

Production and Use of Customizable Agarose Molds for Scaffold-Free Mouse Ovarian Follicle Culture
Published on: October 24, 2025
Current concepts of cell-cycle regulation and its relationship to oocyte maturation, fertilization and embryo
J J Parrish1, C I Kim, I H Bae
1Department of Meat and Animal Science, University of Wisconsin-Madison Madison, WI 53706, USA.
Abstract:
Genetic and biochemical approaches have contributed to an explosion of literature on cell-cycle control. Regulation of the cell-cycle is controlled by a series of kinases and phosphatases. Key control points are during the G(1)-S and G(2)-M transitions. During both transitions, cyclins interact with a specific kinase to allow a cell to pass through that phase. The meiotic maturation of oocytes, fertilization and embryo development are all events influenced by cell-cycle regulation. Understanding cell-cycle control should provide new ways for gamete and embryo biologists to approach culture and development problems.
Related Concept Videos
Oogenesis
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is known...
Oogenesis
Ovarian Cycle
Folliculogenesis
The Cell Cycle Control System
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and function at the cell...
The Cell Cycle Control System

