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Published on: March 14, 2017
Regional mapping of the parathyroid hormone gene (PTH) by cytogenetic and molecular studies
H Tonoki1, K Narahara, T Matsumoto
1Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
Abstract:
The locus for the human parathyroid hormone gene (PTH) was assigned to a region proximal to 11p15.4 using restriction fragment length polymorphisms and gene dose studies performed on a patient with the Beckwith-Wiedemann syndrome accompanied with a chromosome abnormality [46,XX,-14,+der(14),t(14;11)(q32.3;p15.3)pat]. Our data suggest that PTH is localized in 11p15.3----p15.1, most likely near the border of the bands 11p15.4 and 11p15.3.
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