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Does a birthday predispose to vascular events?
Gustavo Saposnik1, Akerke Baibergenova, Jason Dang
1Stroke Team, Department of Clinical Neurological Sciences, London Health Sciences Center, University of Western Ontario, Ontario, Canada. gsaposni@uwo.ca
Insights
Birthdays may increase the risk of vascular events like stroke and heart attack. Stress from birthdays could trigger these events, especially in individuals with hypertension.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Vascular events, including stroke, transient ischemic attack (TIA), and acute myocardial infarction (AMI), represent significant public health concerns.
- The influence of specific life events or stressors on the onset of these critical medical conditions requires further investigation.
Purpose of the Study:
- To investigate the potential association between birthdays and the incidence of acute vascular events.
- To determine if birthdays act as a trigger for stroke, TIA, or AMI.
Main Methods:
- A population-based study analyzed emergency department admissions for ischemic stroke, TIA, and AMI in Ontario, Canada, between April 2002 and March 2004.
- Event occurrences were compared to expected daily rates, focusing on the patient's birthday and the surrounding week.
- Statistical analyses included binomial tests and logistic regression, with adjustments for potential confounding factors.
Main Results:
- A statistically significant increase in vascular events, including stroke, TIA, and AMI, was observed on birthdays compared to expected rates.
- Vascular events were more likely to occur on a patient's birthday (Odds Ratio = 1.27).
- This increased likelihood was particularly pronounced in patients with a history of hypertension.
Conclusions:
- The findings suggest that birthdays, potentially due to associated stress, may precipitate vascular events.
- Individuals with predisposing conditions, such as hypertension, may be more vulnerable to these birthday-associated triggers.
Objective:
To examine the influence of birthdays on the onset and course of vascular events such as stroke, TIA, and acute myocardial infarction (AMI).
Methods:
This population-based study included all emergency department (ED) admissions due to ischemic stroke, TIA, or AMI from April 2002 to March 2004 in Ontario, Canada. All cases were identified through the National Ambulatory Care Reporting System. Calculations of daily and weekly numbers of events were centered on the patient's birthday and the week of the birthday. Statistical analyses include binomial tests and logistic regression.
Results:
During the study period, there were 24,315 ED admissions with acute stroke, 16,088 with TIAs, and 29,090 with AMI. The observed number of vascular events during the birthday was higher than the expected daily number of visits for stroke (87 vs 67; p = 0.009), TIA (58 vs 44; p = 0.02), and AMI (97 vs 80; p = 0.027) but not for selected control conditions (asthma, appendicitis, head trauma). Vascular events were more likely to occur on birthday (242 vs 191; odds ratio [OR] = 1.27). No significant differences were observed during the birthday week for any of the conditions. Multivariate logistic regression showed that birthday vascular events were more likely to occur in patients with a history of hypertension (OR = 1.88; 95% CI 1.09 to 3.24). Sensitivity analyses with alternative definitions of birthday week did not alter the results.
Conclusions:
Stress associated with birthdays may trigger vascular events in patients with predisposing conditions.
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