Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 13, 2026

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Heavy water detection using ultra-high-Q microcavities.

Andrea M Armani1, Kerry J Vahala

  • 1Department of Applied Physics, California Institute of Technology, 1200 East California Boulevard, M/C 128-95, Pasadena, 91125, USA.

Optics Letters
|May 27, 2006
PubMed
Summary

Ultra-high-Q optical microcavities can distinguish chemically similar species. Researchers developed a sensitive Deuterium Oxide (D2O) detector using this technology, improving detection limits by an order of magnitude.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Open-Source Benchtop Magnetophotometer for Characterizing the Magnetic Susceptibility of Suspended Nanoparticles.

Analytical chemistry·2026
Same author

Denoising of fluorescence lifetime imaging data via principal component analysis.

Scientific reports·2025
Same author

Magnetically Tunable Hydrogel for Biofilm Control.

ACS applied bio materials·2025
Same author

Enhanced fluorescence lifetime imaging microscopy denoising via principal component analysis.

bioRxiv : the preprint server for biology·2025
Same author

Synthesis and Characterization of Superparamagnetic Iron Oxide Nanoparticles: A Series of Laboratory Experiments.

Journal of chemical education·2024
Same author

Nondestructive, quantitative viability analysis of 3D tissue cultures using machine learning image segmentation.

APL bioengineering·2024

Area of Science:

  • Optics
  • Analytical Chemistry
  • Materials Science

Background:

  • Ultra-high-Q optical microcavities (Q > 10^7) are valuable for differentiating chemically similar substances.
  • Optical absorption differences between heavy water (Deuterium Oxide, D2O) and regular water (H2O) affect microcavity quality factors.
  • Previous methods lacked the sensitivity required for detecting low concentrations of D2O.

Purpose of the Study:

  • To develop a sensitive detector for Deuterium Oxide (D2O) in water.
  • To leverage the optical properties of microcavities for chemical sensing.
  • To demonstrate an improved method for distinguishing H2O and D2O.

Main Methods:

  • Utilized ultra-high-Q optical microcavities as sensing elements.
  • Measured the quality factor (Q) of resonators immersed in H2O and D2O.

More Related Videos

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

In Situ Characterization of Boehmite Particles in Water Using Liquid SEM
11:59

In Situ Characterization of Boehmite Particles in Water Using Liquid SEM

Published on: September 27, 2017

Related Experiment Videos

Last Updated: Jul 13, 2026

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Implementation of a Reference Interferometer for Nanodetection
16:11

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

In Situ Characterization of Boehmite Particles in Water Using Liquid SEM
11:59

In Situ Characterization of Boehmite Particles in Water Using Liquid SEM

Published on: September 27, 2017

  • Focused measurements at a wavelength of 1,300 nm where optical absorption differences are most pronounced.
  • Main Results:

    • Observed significantly lower quality factors for resonators in H2O compared to D2O.
    • Achieved detection of D2O concentrations as low as 0.0001% (1 part in 10^6 by volume).
    • Demonstrated reversible detection through cyclic introduction and flushing of D2O.

    Conclusions:

    • Ultra-high-Q optical microcavities offer a highly sensitive method for D2O detection.
    • The developed technique provides an order of magnitude improvement in sensitivity over existing methods.
    • The microcavity-based sensor shows potential for real-time, reversible monitoring of D2O concentrations.