Related Experiment Video
Updated: Aug 8, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Comparison of two delivery methods of local anesthetic distribution after intra-articular knee injection
Richard E Jones1, Jamie Gottlieb, Bryan Kaiser
1Department of Orthopedic Surgery, Veterans Administration Hospital, Dallas, TX, USA.
Abstract:
We studied the intra-articular distribution of radiopaque dye to compare the efficacy of a continuous low-volume infusion with an intermittent high-volume bolus infusion. Knee arthroscopy patients were randomized with 10 cc of dye infused over 2.5 hours versus 10 cc bolus of dye. Radiographs were independently evaluated. Eleven knees (low-volume infusion) filled an average of 3 of 7 compartments, while 10 knees (bolus group) had complete filling of all seven compartments (P < .001). This study supports high-volume bolus injections of local anesthetics to achieve consistent distribution to all knee compartments while enhancing pain control.
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