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Updated: Aug 8, 2026

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
Non-immune thrombocytopenia responsive to antiretroviral therapy and HIV-2 infection
Jaime R Torres1, Maria A Torres-Viera, Jorg Schupbach
1Infectious Diseases Section, Topical medicine Institute, Universidad Central de Venezuela, Caracas, Venezuela. torresj@post.com
Abstract:
HIV-2 infection was documented for the first time in Venezuela, in a heterosexual couple. Two identical subtype A viral strains exhibiting multiple resistance mutations to antiretroviral drugs were identified. One of the patients suffered from progressive non-immune thrombocytopenia and extranodal NK/T-cell type lymphoma, an association not previously described for HIV-2. His hematological condition promptly improved after onset of an effective antiretroviral therapy.
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