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Updated: Aug 8, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
Pregnancy in perinatally HIV-infected adolescents
Amy B Levine1, Erika Aaron, Jill Foster
1Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA. alevine@drexelmed.edu
Background:
Long-term survival of patients with congenital human immunodeficiency virus (HIV) infection has resulted in a growing cohort of perinatally infected adolescents and young adults who are sexually active and becoming pregnant.
Cases:
Two cases are presented to report our management of pregnancies resulting from unprotected sexual practices in perinatally HIV-infected adolescents who were HIV serodiscordant. An integrated approach, involving the specialties of pediatrics, obstetrics and gynecology, and infectious disease, along with social services, was used to provide comprehensive care to these patients.
Conclusion:
There is a need to address reproductive health issues, especially risky sexual behaviors, in adolescents who are HIV infected.
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