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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Use of the TandemHeart Percutaneous Ventricular Assist Device to Support Patients Undergoing High-Risk Percutaneous
Biswajit Kar1, Matthew Forrester, Courtney Gemmato
1Texas Heart Institute at St. Luke's Espiscopal Hospital, P.O. Box 20345, Houston, TX, 77225—0345, USA. temppub@heart.thi.tmc.edu.
Insights
The TandemHeart percutaneous ventricular assist device (pVAD) offers hemodynamic support during high-risk percutaneous coronary intervention (PCI) for patients ineligible for surgery. This approach shows promise for improving outcomes in complex cardiovascular cases.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Coronary artery bypass grafting (CABG) is standard for unprotected left main coronary artery disease.
- Severe comorbidities can make CABG unsuitable, necessitating alternative treatments.
- Percutaneous coronary intervention (PCI) in such cases presents high risks.
Purpose of the Study:
- To evaluate the use and efficacy of the TandemHeart percutaneous ventricular assist device (pVAD) for hemodynamic support during high-risk PCI.
- To assess the safety and feasibility of pVAD implementation in patients with severe comorbidities.
Main Methods:
- The TandemHeart pVAD was utilized for hemodynamic support in 5 consecutive patients undergoing high-risk PCI.
- Patients were ineligible for CABG due to severe comorbidities.
- Device insertion and initiation of circulatory support were performed prior to percutaneous revascularization.
Main Results:
- Successful pVAD insertion and support initiation without immediate complications in all 5 cases.
- Percutaneous revascularization was successfully completed with pVAD support (average flow 3 L/minute).
- Four patients recovered uneventfully after short-term pVAD support; one patient experienced mortality due to heart failure post-procedure.
Conclusions:
- The pVAD can provide adequate hemodynamic protection during high-risk PCI.
- This device may improve morbidity and mortality rates for high-risk patients.
- Further research is warranted to explore the full potential of pVAD in complex PCI scenarios.
Abstract:
OBJECTIVES: We describe our experience in using the TandemHeart percutaneous ventricular assist device (pVAD) during high-risk percutaneous coronary intervention (PCI). BACKGROUND: Coronary artery bypass grafting (CABG) is the preferred treatment for disease in an unprotected left main coronary artery or left main equivalent. However, severe comorbidities may preclude surgery in some patients. In these cases, PCI is also often a high-risk procedure. The pVAD is designed to provide circulatory support during high-risk PCI. METHODS AND RESULTS: We used the pVAD for hemodynamic support during PCI in 5 consecutive patients who were ineligible for CABG because of severe comorbidities. In all 5 cases, the device was inserted and support initiated without complications. Percutaneous revascularization was successfully performed with pVAD support (approximately 3 L/minute). Four patients were supported for an average of 107 minutes, the pVAD being withdrawn shortly after PCI; all 4 patients recovered uneventfully. The fifth patient required support for 48 more hours after the procedure because of poor ventricular function. He died of heart failure and severe mitral regurgitation 10 days after pVAD withdrawal. CONCLUSIONS: The pVAD may provide sufficient circulatory support for hemodynamic protection during high-risk PCI, thus improving morbidity and mortality and broadening the therapeutic options for high-risk patients. Further investigation of this device is warranted.
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