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Mouse Sperm Cryopreservation and Recovery using the I·Cryo Kit
Published on: December 12, 2011
Sperm cryopreservation in male infertility due to genetic disorders
1Andrology Unit, Department of Clinical Physiopathology, Viale Pieraccini, 6, Firenze, Italy. c.krausz@dfc.unifi.it
Abstract:
Certain chromosomal and genetic anomalies, such as Klinefelter syndrome (47,XXY) and Y chromosome microdeletions, have been reported as potential causes of a progressive impairment of spermatogenesis. In these cases cryoconservation of ejaculated or testicular sperm represent a valuable tool for the preservation of fertility. However, dealing with genetic disorders, the transmission of genetic anomalies has to be taken into consideration. It is therefore important to be aware about the clinical importance and the related genetic risks of these anomalies. In this article we describe the clinical significance of these diseases.
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