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[DNA diagnosis in veterinary medicine: I. DNA fingerprinting]
C P Schelling1, P E Thomann, U Hübscher
1Institut für Pharmakologie und Biochemie, Veterinärmedizinische Fakultät, Universität, Zürich.
Schweizer Archiv Fur Tierheilkunde
|January 1, 1991
Abstract:
With the development of recombinant DNA-technology during the last 15 years, it became possible to analyse genetic variability directly at the level of genomic DNA. Restriction-Fragment-Length-Polymorphism (RFLP) and Highly-Variable-Regions (HVRs) lead to the development of new genetic markers, which can be used for the localization of normal and mutated genes. Some polymorphisms are hypervariable and can therefore be applied to carry out DNA-fingerprints thus identifying individuals from man and animals.