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Updated: Aug 8, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Foreign body giant cell reaction to polytetrafluoroethylene used as interposition material in scaphoid-trapezium
M Udeshi1, H Bangash, J Gagliardi
1Department of Radiology, St Vincent's Medical Center, Bridgeport, Connecticut 06606, USA. michelleudeshi@hotmail.com
Abstract:
We present the case of a 54-year-old woman who presented with a one and a half-year history of persistent pain at the base of her right thumb. A scaphoid-trapezium interposition arthroplasty with polytetrafluoroethylene was carried out in an effort to improve function and decrease the patient's persistent pain. Approximately 7 years after surgery, she began to complain of increasing pain and radiographs showed extensive osteolytic changes, consistent with a foreign body giant cell reaction.
