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Proteomics of breast cancer: principles and potential clinical applications

François Bertucci1, Daniel Birnbaum, Anthony Goncalves

  • 1Centre de Recherche en Cancérologie de Marseille, Département d'Oncologie Moléculaire, Institut Paoli-Calmettes, IPC, and UMR599 INSERM, 13009 Marseille, France. bertuccif@marseille.fnclcc.fr

Molecular & Cellular Proteomics : MCP
|May 31, 2006
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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...