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Updated: Aug 8, 2026
Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head
Published on: January 3, 2020
[Diagnosis and treatment of primitive neuroectodermal tumors of pancreas]
Xin-ting Sang1, Nai-xin Liang, Yi-lei Mao
1Department of Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China. sangxt1963@yahoo.com
Objective:
To improve the diagnosis and treatment of primitive neuroectodermal tumors (PNET) of the pancreas.
Methods:
One patient with PNET of the pancreas was reported in this article. The corresponding literatures on the diagnosis and treatment was reviewed.
Results:
The patient was diagnosed as pancreatic PNET by her clinical, microscopic, and immunohistochemical features as well as cytogenetic analysis after the resection of the tumor located in the uncinate process in PUMC Hospital. Radiochemotherapy was given after the operation for 8 months and no recurrence was observed. Since PNET of pancreas have no specific clinical symptoms and most patients have jaundice and/or abdominal pain, the diagnosis depended on the immunohistochemical features of positive P30/32(MIC2) and at least two of the neural markers. The cytogenetic analysis showed translocation mainly harbored the characteristic t (11; 22) (q24; q12). Since pancreatic PNET were highly aggressive, early chemotherapy, close follow-up, and immediate surgical interventions were required as early as possible.
Conclusion:
PNET can occur in pancreas, and diagnosis and treatment should be made as early as possible to improve the outcome.
