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[Rhabdomyolysis in a bodybuilder using steroids].

J M A Daniels1, D J van Westerloo, O M de Hon

  • 1Onze Lieve Vrouwe Gasthuis, afd. Interne Geneeskunde, Amsterdam. j.m.a.daniels@olvg.nl

Nederlands Tijdschrift Voor Geneeskunde
|June 1, 2006
PubMed
Summary

Anabolic steroid abuse in bodybuilders can lead to acute rhabdomyolysis, a severe muscle breakdown. Prompt medical intervention with fluids and urine alkalinization is crucial for recovery and preventing kidney damage.

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Area of Science:

  • Sports Medicine
  • Toxicology
  • Endocrinology

Background:

  • Anabolic-androgenic steroid (AAS) use is prevalent among athletes seeking performance enhancement.
  • Concurrent use of other performance-enhancing drugs (PEDs) like clenbuterol and thyroid hormones is common in bodybuilding.
  • Acute medical emergencies related to PED use require prompt recognition and management.

Observation:

  • A 34-year-old male bodybuilder presented with fever, vomiting, and muscle cramps during a training session.
  • The patient reported recent use of multiple anabolic steroids (dehydro-chloro-methyltestosterone, boldenone, trenbolone), clenbuterol, and liothyronine.
  • Laboratory results indicated massive rhabdomyolysis, a serious condition of muscle breakdown.

Findings:

  • The patient experienced severe muscle cramps and elevated creatine kinase levels indicative of rhabdomyolysis.

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  • Treatment involved intravenous fluid resuscitation and sodium bicarbonate to alkalinize the urine.
  • The patient demonstrated a rapid recovery with no lasting renal impairment.

    • Implications:

    • This case highlights the acute risks associated with polydrug use in bodybuilding, including severe rhabdomyolysis.
    • Physicians should inquire about doping practices in athletes presenting with unexplained acute symptoms.
    • Awareness of potential doping-related health emergencies is vital for timely and effective patient care.