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Apical aneurysm in a patient with apical hypertrophic cardiomyopathy
Constantin B Marcu1, Ajoy Kapoor, Thomas J Donohue
1Vrije University Medical Center, Amsterdam, The Netherlands. bogmarcu@pol.net
Insights
Apical hypertrophic cardiomyopathy (AHC) is a rare heart condition affecting the left ventricle apex. This case highlights AHC with prior myocardial infarction and ischemia despite normal coronary arteries, offering insights into diagnosis and management.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Apical hypertrophic cardiomyopathy (AHC) is a distinct variant of hypertrophic cardiomyopathy (HCM).
- AHC is characterized by predominant hypertrophy of the left ventricular apex.
- Typical AHC features include specific ECG abnormalities and cardiac morphology.
Observation:
- This report details a patient diagnosed with AHC.
- The patient exhibited evidence of prior myocardial infarction and apical aneurysm.
- Myocardial ischemia was detected via radionuclide scanning.
Findings:
- The patient presented with angiographically normal coronary arteries.
- Electrocardiographic, echocardiographic, and hemodynamic findings were characteristic of AHC.
- The case underscores a complex presentation of AHC with coexisting cardiac events.
Implications:
- Understanding AHC variants is crucial for accurate diagnosis and treatment.
- This case expands the spectrum of AHC presentations.
- Further research into the pathophysiology and management of AHC is warranted.
Abstract:
Apical hypertrophic cardiomyopathy (AHC) is a variant of hypertrophic cardiomyopathy (HCM) in which the hypertrophy predominantly involves the left ventricular apex. The typical features of AHC include giant negative T waves in the precordial ECG leads, a spade-like configuration of the left ventricle at end-systole, the absence of an outflow tract pressure gradient, and mild symptoms. We present a patient with AHC, evidence of prior myocardial infarction with aneurysm of the apical region, and myocardial ischemia on radionuclide scanning despite angiographically normal coronary arteries. The characteristic electrocardiographic, echocardiographic, hemodynamic and angiographic findings as well as prognosis and treatment options are discussed.
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