Related Experiment Video

Updated: Jul 17, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
07:32

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles

Published on: August 28, 2015

[Dependence of antimicrobial effect of micelle-capsulated therapeutics on the micelle size]

E M Chumakov, B N Khlebtsov, N G Khlebtsov

    Antibiotiki I Khimioterapiia = Antibiotics and Chemoterapy [Sic]
    |June 1, 2006
    PubMed

    More Related Videos

    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles09:57

    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

    Published on: December 23, 2016

    Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis08:01

    Synthesis of Monocyte-targeting Peptide Amphiphile Micelles for Imaging of Atherosclerosis

    Published on: November 17, 2017

    Related Concept Videos

    Micelles01:30

    Micelles

    Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
    Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

    Factors Affecting Dissolution: Particle Size and Effective Surface Area

    Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are employed to...
    Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

    Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry

    Orally administered drugs primarily enter the systemic circulation via passive diffusion through the intestinal membranes. The drug's absorption is influenced by drug stability in the gastrointestinal GI tract, membrane permeability, the surface area available for absorption, luminal drug concentration, and residence time in the lumen. Drug permeability can be enhanced by adjusting the lipophilicity, polarity, or molecular size of the drug, promoting its passive transport across intestinal...
    Bioavailability Enhancement: Drug Solubility Enhancement01:16

    Bioavailability Enhancement: Drug Solubility Enhancement

    Bioavailability is a critical factor in determining a drug's effectiveness. It refers to the proportion of a drug that enters the circulation when introduced into the body and is, as a result, able to have an active effect. Enhancing bioavailability is essential for drugs with poor solubility, as it can significantly impact their therapeutic efficacy. Various methods are employed to increase the solubility of drugs, thereby enhancing their bioavailability.Micronization and nanonization are...
    Modified-Release Drug Delivery Systems: Influencing Factors01:20

    Modified-Release Drug Delivery Systems: Influencing Factors

    Modified-release drug delivery systems are designed to optimize the therapeutic effect of drugs by minimizing side effects, reducing the dosage required, and controlling drug release to align with pharmacokinetic and pharmacodynamic needs. The system depends on two key factors: the drug's release from the formulation and its movement through the body to the target site. Unlike conventional dosage forms, where absorption is the limiting step, the rate of drug release is the key determinant in...
    Antimicrobial Effectiveness01:28

    Antimicrobial Effectiveness

    The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...