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Updated: Aug 8, 2026
A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Monotherapy with carbon ion radiation for localized prostate cancer
Jun Shimazaki1, Koichiro Akakura, Hiroyoshi Suzuki
1Department of Urology, Graduate School of Medicine, Chiba University, Chuo-ku, Chiba-shi 260-8670, Japan. shimajun@opal.famille.ne.jp
Background:
Radiation treatment for localized prostate cancer has become a prominent choice of monotherapy, and carbon ion beam is a powerful means for this purpose.
Methods:
In total, 37 patients with localized prostate cancer were treated by monotherapy with carbon ion radiation and the outcome, more than 4 years later, was followed.
Results:
PSA relapse-free survival was overall 85%, 5 years after radiation, and 96% in low-risk patients. Local control was mostly achieved, and no cancer-specific death was obtained. Except in cases of relapse, 1.0 ng/ml or less of PSA was shown in 78%, 3 years after radiation. Half of biopsy specimens out of 12 cases revealed non-viable or no cancer cells after a rather short time from treatment.
Conclusion:
Monotherapy with carbon ion radiation may be an excellent treatment for localized prostate cancer with low risk.
