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Aging and HIV infection.

Rakhi Kohli1, Robert S Klein, Ellie E Schoenbaum

  • 1Division of Geographic Medicine and Infectious Disease, Department of Medicine, Tufts-New England Medical Center, 750 Washington Street #41, Boston, MA 02111, USA. rkohli@tufts-nemc.org

Journal of Urban Health : Bulletin of the New York Academy of Medicine
|June 1, 2006
PubMed
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Highly active antiretroviral therapy (HAART) has improved HIV prognosis, but long-term health risks for aging individuals are emerging. Further research is needed on the effects of chronic HIV and treatments on older adults.

Area of Science:

  • Geriatrics
  • Infectious Diseases
  • Pharmacology

Background:

  • Highly active antiretroviral therapy (HAART) significantly improved HIV patient survival since 1995.
  • Increased longevity in HIV-infected individuals presents new long-term health challenges.
  • The long-term impacts of HIV infection and antiretroviral drugs are not fully understood.

Purpose of the Study:

  • To discuss the emerging health issues faced by aging HIV-infected populations.
  • To identify key areas for future research concerning long-term HIV management.

Main Methods:

  • This paper is a discussion and review of current knowledge.
  • It synthesizes existing data on HIV, aging, and antiretroviral therapy.

Main Results:

Related Experiment Videos

  • Aging HIV-infected individuals may face unique challenges.
  • Potential long-term effects include psychiatric, neurocognitive, metabolic, and hormonal disorders.
  • Chronic exposure to HIV and antiretroviral agents may influence these conditions.

Conclusions:

  • HIV specialists must prepare for the complex health needs of older HIV patients.
  • Further research is critical to understand and manage the long-term consequences of HIV and its treatment.