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Epoetin-induced pure red cell aplasia successfully treated with androgens
Maria Dolores Sánchez de la Nieta1, Guadalupe Caparrós, Francisco Rivera
1Nephrology Unit, Alarcos Hospital, Ciudad Real, Spain.
Pure red cell aplasia (PRCA) is a severe, non-regenerative form of anaemia, with selective erythroid aplasia of the bone marrow. It appears as a severe complication of treatment for anaemia of end-stage renal insufficiency with erythropoiesis-stimulating agents. There is no definite treatment. We described for the first time a patient with chronic renal failure and antibody-mediated PRCA successfully treated with androgens.
Pure red cell aplasia (PRCA) is a severe, non-regenerative form of anaemia, with selective erythroid aplasia of the bone marrow. It appears as a severe complication of treatment for anaemia of end-stage renal insufficiency with erythropoiesis-stimulating agents. There is no definite treatment. We described for the first time a patient with chronic renal failure and antibody-mediated PRCA successfully treated with androgens.
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