Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acid-base balance in peritoneal dialysis.

R Dell'Aquila1, M P Rodighiero, E Spanò

  • 1Department of Nephrology, Dialysis and Transplantation, St. Bortolo Hospital, Vicenza, Italy. robert.dellaquila@ulssvicenza.it

Journal of Nephrology
|June 1, 2006
PubMed
Summary

Peritoneal dialysis patients rely on dialysate for base replenishment. Bicarbonate-buffered solutions offer advantages over lactate-buffered solutions for maintaining base balance in these patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of resistance to pirimiphos-methyl (an organophosphate insecticide) in Culex pipiens pipiens (Diptera: Culicidae) from Northern and Southern Tunisia.

Tropical biomedicine·2021
Same author

Multiple resistance mechanisms associated with low pirimifos-methyl resistance in Culex pipiens pipiens in three populations of Tunisia.

Tropical biomedicine·2021
Same author

Impacts of agricultural practices on pyrethroid resistance in Culex pipiens pipiens, an important vector of human diseases, from Tunisia.

Tropical biomedicine·2021
Same author

sRAGE: a prognostic factor for mortality in end-stage renal disease patients on dialysis.

Journal of biological regulators and homeostatic agents·2019
Same author

Elevated Levels of Procalcitonin and Interleukin-6 are Linked with Postoperative Complications in Cardiac Surgery.

Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society·2017
Same author

Nonvitamin K-dependent oral anticoagulants (NOACs) in chronic kidney disease patients with atrial fibrillation.

Thrombosis research·2017

Area of Science:

  • Nephrology
  • Biochemistry

Background:

  • Patients with non-functioning kidneys require alkali replenishment through dialysis solutions.
  • Peritoneal dialysis (PD) patients self-regulate body base balance via feedback between plasma bicarbonate and dialysate base gain.
  • Dialysate base gain is crucial for PD patients, counteracting metabolic acid production and depending on peritoneal buffer fluxes.

Purpose of the Study:

  • To compare the efficacy of bicarbonate-buffered versus lactate-buffered peritoneal dialysis solutions.
  • To analyze the self-regulatory mechanisms of body base balance in PD patients.

Main Methods:

  • Analysis of peritoneal buffer fluxes (lactate reabsorption vs. bicarbonate loss).
  • Monitoring of plasma bicarbonate concentration and dialysate base gain.

Related Experiment Videos

  • Comparison of bicarbonate and lactate buffered PD solutions.

    • Main Results:

    • Bicarbonate-buffered PD solutions demonstrate advantages over conventional lactate-buffered solutions.
    • The body base balance in PD patients is regulated by the interplay of plasma bicarbonate and dialysate base gain.
    • Dialysate base gain is the sole buffer source for PD patients, essential for managing metabolic acid production.

    Conclusions:

    • Bicarbonate-buffered PD solutions offer benefits for PD patients.
    • Understanding the feedback mechanisms is key to managing base balance in PD.
    • Optimizing dialysate composition is important for patient outcomes.