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Updated: Jul 4, 2026

Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition
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Transcription factor Ets-1 is essential for mesangial matrix remodeling

M Mizui1, Y Isaka, Y Takabatake

  • 1Department of Nephrology, Osaka University Graduate School of Medicine (A8), Suita, Japan.

Kidney International
|June 2, 2006
PubMed
Summary

The transcription factor Ets-1 helps prevent abnormal protein buildup in the kidneys by promoting the breakdown of extracellular matrix (ECM). Restoring Ets-1 levels reduces kidney scarring in glomerular diseases.

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