Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neuroproteomics - the tasks lying ahead.

Michael Becker1, Jens Schindler, Hans Gerd Nothwang

  • 1Abteilung Tierphysiologie, Fachbereich Biologie, Technische Universität Kaiserslautern, Germany.

Electrophoresis
|June 2, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevention of Heart Failure in Women: An Expert Consensus Statement on Sex-Specific Risk Factors.

European journal of heart failure·2026
Same author

Screen for Tissue-Specific Markers of Drug-Induced Phospholipidosis Using Mass Spectrometry Imaging.

Journal of the American Society for Mass Spectrometry·2026
Same author

Usage of and Satisfaction with Artificial Intelligence-Generated Draft Replies to Patient Portal Messages.

Applied clinical informatics·2026
Same author

Effort, timing and choice: a refined rodent effort choice task with excellent sensitivity to dopamine modulators.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Managing pectin: Cell wall integrity maintenance in the streptophyte alga, Penium margaritaceum.

Annals of botany·2026
Same author

Predicting developmental outcomes in adulthood using domain-specific development in adolescence.

Developmental psychology·2026
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

Neuroproteomics offers insights into brain function by analyzing proteins. Current methods excel at identifying protein modifications and interactions, but global profiling requires further development.

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Biochemistry

Background:

  • The brain's complexity presents a significant challenge to understanding its function.
  • Neuroproteomics is an emerging field aiming to elucidate molecular mechanisms of brain function.
  • Advances in transcriptomics and proteomics provide new tools for neuroscientific research.

Purpose of the Study:

  • To review the cellular, molecular, and functional complexity of the brain.
  • To survey transcriptomics and proteomics technologies relevant to neuroscience.
  • To evaluate the strengths and weaknesses of current proteomics techniques for brain studies.

Main Methods:

  • Review of existing literature on brain complexity.
  • Analysis of transcriptomics and proteomics technologies.

Related Experiment Videos

  • Evaluation of widely used proteomics techniques (e.g., mass spectrometry).

    • Main Results:

    • Neuroproteomics should prioritize identifying posttranslational modifications and protein-protein interactions.
    • Characterization of highly purified subproteomes is a current strength of neuroproteomics.
    • Global protein expression profiling in neuroscience requires further technological advancement for increased coverage.

    Conclusions:

    • Neuroproteomics is a valuable approach for understanding brain molecular mechanisms.
    • Strategic application of current neuroproteomics techniques is crucial for hypothesis generation.
    • Continued development of proteomics technologies is essential for comprehensive brain analysis.