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Related Experiment Videos

Assisted reproductive technology: both sides now.

Anthony P Cheung1

  • 1IVF Program, University of British Columbia Centre for Reproductive Health, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Vancouver, BC, Canada V5Z 1M9. apcheung@interchange.ubc.ca

The Journal of Reproductive Medicine
|June 3, 2006
PubMed
Summary
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Assisted reproductive technology (ART) increases pregnancy success but also multiple births, risking infant health. Reducing embryo transfers can improve perinatal outcomes for healthier singleton births.

Area of Science:

  • Reproductive Medicine
  • Perinatal Health
  • Assisted Reproductive Technology

Background:

  • Assisted reproductive technology (ART) has improved pregnancy success over two decades.
  • ART use is associated with a rise in multiple births, increasing risks for perinatal well-being.
  • Concerns about birth defects and developmental issues necessitate scrutiny of ART's adverse perinatal outcomes.

Purpose of the Study:

  • To summarize the prevalence of multiple pregnancies and associated risks with ART.
  • To discuss potential approaches for minimizing ART-related perinatal complications.
  • To highlight the balance between ART success rates and adverse perinatal outcomes.

Main Methods:

  • Review of literature on ART, multiple pregnancies, and perinatal outcomes.

Related Experiment Videos

  • Analysis of risks including low birth weight, birth defects, and developmental sequelae.
  • Discussion of strategies to mitigate adverse perinatal outcomes.

    • Main Results:

    • Multiple pregnancies resulting from ART significantly increase risks of prematurity, low birth weight, and perinatal mortality.
    • ART is linked to concerns regarding birth defects and long-term developmental sequelae.
    • Reducing embryo transfers is a key strategy to minimize adverse outcomes from multiple births.

    Conclusions:

    • ART offers increased pregnancy success but requires careful consideration of perinatal complications.
    • Minimizing multiple births through strategies like single embryo transfer is crucial for improving infant health.
    • Refinements in ART techniques aim for equivalent pregnancy success with singleton live births.