Related Experiment Video
Updated: Aug 8, 2026

Induction of Cerebral Arterial Gas Embolism in Rat
Published on: October 18, 2024
Hemorrhagic gastritis and gas emboli after ingesting 3% hydrogen peroxide
Jeong Mi Moon1, Byeong Jo Chun, Yong Il Min
1Department of Emergency Medicine, Chonnam National University Hwasun Hospital and Chonnam Medical School, Gwangju, South Korea.
Abstract:
It is well known that ingestion of low concentrations of hydrogen peroxide is usually nontoxic; this does not produce gas embolism and is only a mild irritant to the gastrointestinal tract. We report the case of a 25-year-old woman who ingested one mouthful of 3% hydrogen peroxide and presented to the Emergency Department with persistent vomiting and epigastric pain. The radiographic evaluation found portal venous gas emboli. In addition, upper gastrointestinal endoscopy performed 2 h after ingestion revealed diffuse hemorrhagic gastritis. She showed a decrease of hemoglobin concentration and a positive test result for occult blood in stool. She was observed for 14 days and discharged. Follow-up endoscopy showed erythematous gastritis. This case illustrates that a low concentration of hydrogen peroxide can cause portal venous gas embolism and severe gastrointestinal injuries even if only a small amount is ingested.
Related Concept Videos
Peptic Ulcer
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Peroxisomes
Gastritis II: Pathophysiology
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Autoxidation of Ethers to Peroxides and Hydroperoxides