Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone substitution in revision hip replacement.

C Nich1, L Sedel

  • 1Department of Orthopaedic Surgery, Lariboisiere Hospital, University of Paris VII, Paris, France. chrnich@gmail.com

International Orthopaedics
|June 3, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synovial Biomarkers C-Reactive Protein and Calprotectin for Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Multicenter Evaluation.

The Journal of arthroplasty·2025
Same author

Dalbavancin-resistant <i>Staphylococcus epidermidis in vivo</i> selection following a prosthetic joint infection: phenotypic and genomic characterization.

JAC-antimicrobial resistance·2024
Same author

Effect of achieving bone sterilisation on bone architecture and bone marrow, in an experimental rabbit model of osteomyelitis caused by carbapenemase-producing Enterobacterales.

International journal of antimicrobial agents·2023
Same author

Does partial tear repair of adjacent tendons improve the outcome of supraspinatus tendonfull-thickness tear reinsertion?

Orthopaedics & traumatology, surgery & research : OTSR·2014
Same author

Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement.

Journal of the Royal Society, Interface·2014
Same author

Alumina on alumina total hip arthroplasty in patients under 50 years of age.

Hip international : the journal of clinical and experimental research on hip pathology and therapy·2013
Same journal

Letter to the editor regarding "Bunionette or artistic convention? Reconsidering fifth toe varus in the Renaissance sculpture Adam by Tullio Lombardo".

International orthopaedics·2026
Same journal

Zone-specific acromial cortical thickening after reverse shoulder arthroplasty.

International orthopaedics·2026
Same journal

The rise of green orthopaedics: a bibliometric mapping and thematic evaluation of the global research landscape.

International orthopaedics·2026
Same journal

Patterns of blood cobalt levels after metal-on-metal total hip arthroplasty, predictors of elevated levels, and associations with clinical symptoms.

International orthopaedics·2026
Same journal

Oncological outcomes and clinical efficacy of uniportal endoscopic technique in the treatment of benign bone tumours and tumour-like lesions adjacent to limb joints: a retrospective study.

International orthopaedics·2026
Same journal

Time neutrality and reduced ecological burden - handheld robotic-assisted total knee arthroplasty improves operating room efficiency compared with manual total knee arthroplasty.

International orthopaedics·2026
See all related articles

This study shows synthetic bone substitutes like calcium phosphate ceramic (CPC) effectively reconstruct femoral bone defects during hip revision surgery. Results indicate good functional outcomes and bone stock restoration in the short to mid-term.

Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Bone Regeneration

Background:

  • Femoral bone defects are a common challenge in revision hip arthroplasty.
  • Restoring bone stock is crucial for successful revision surgery outcomes.
  • Synthetic bone substitutes offer a potential solution for complex bone voids.

Purpose of the Study:

  • To evaluate the preliminary efficacy of calcium phosphate ceramic (CPC) for femoral peri-prosthetic bone defect reconstruction.
  • To assess functional outcomes and bone integration following hip revision with CPC.
  • To report complications and radiographic findings associated with CPC use.

Main Methods:

  • Retrospective evaluation of 21 femoral revisions in 20 patients with SOFCOT grade II or III bone defects.

Related Experiment Videos

  • Reconstruction using impacted calcium phosphate ceramic (CPC) granules, alone or with allograft/autograft.
  • Standard femoral stem implantation with modern cementing techniques.
  • Assessment using Merle d'Aubigné score and radiographic evaluation at a mean 36-month follow-up.

    • Main Results:

    • 90% of hips achieved good or very good functional outcomes (Merle d'Aubigné score).
    • Radiographic evidence of direct bone bonding with CPC was observed in 17 cases.
    • Two cases of diaphyseal femoral fracture and two re-revisions (aseptic loosening, septic recurrence) occurred.
    • Limited stem subsidence (5-8 mm) was noted in two cases.

    Conclusions:

    • Impacted CPC, with or without bone graft, can restore femoral bone stock in revision hip replacement in the short to mid-term.
    • CPC demonstrates potential for direct bone integration, aiding in bone defect reconstruction.
    • Further long-term studies are warranted to confirm the durability and efficacy of CPC in these complex cases.