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Updated: Aug 8, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
[Multivessel percutaneous coronary interventions. When incomplete revascularization may represent a therapeutic
Fabrizio Ugo1, Emilia Solinas, Diego Ardissino
1UO Cardiologia, Dipartimento del Cuore, Azienda Ospedaliero-Universitaria, Parma. ugo.fabrizio@libero.it
For ischemic heart disease patients with multivessel disease, staged percutaneous coronary intervention (PCI) is often preferred over complete revascularization. This approach minimizes risks associated with immediate multi-vessel PCI.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Prognosis for ischemic heart disease is similar for surgery and percutaneous revascularization.
- Multivessel disease prompts search for aggressive percutaneous coronary intervention (PCI) strategies.
- Debate exists between complete revascularization and culprit-only vessel PCI.
Purpose of the Study:
- To evaluate the optimal PCI strategy for patients with multivessel disease.
- To analyze the risks and benefits of complete versus staged revascularization.
- To inform clinical decision-making in acute coronary syndromes.
Main Methods:
- Review of current American and European guidelines for PCI.
- Analysis of treatment strategies for ST-elevation and non-ST-elevation myocardial infarction.
- Consideration of factors influencing PCI approach, including patient anatomy and procedural risks.
Main Results:
- Guidelines recommend culprit-only PCI for ST-elevation myocardial infarction with multivessel disease.
- PCI of non-culprit lesions is guided by ischemia evidence during follow-up.
- Individualized approach for non-ST-elevation myocardial infarction allows for single or multivessel PCI based on anatomy.
Conclusions:
- Staged revascularization is supported by risks like endothelial dysfunction, post-procedural infarction, contrast nephropathy, radiation exposure, and costs.
- Individualized PCI strategies are crucial for optimal patient outcomes.
- Minimizing procedural risks favors staged approaches when appropriate.
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