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Synthesis and Characterization of Functionalized Metal-organic Frameworks
Published on: September 5, 2014
6,6'-Dibromo-4,4'-di(hexoxymethyl)-2,2'- bipyridine: a new solubilizing building block for macromolecular and
1Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota 58105-5516, USA.
The Journal of Organic Chemistry
|June 6, 2006
Abstract:
Although brominated bipyridines and terpyridines are highly desirable synthetic building blocks for both ligand design and macro- or supramolecular applications, few such synthetic precursors have been reported that include much-needed solubilizing groups. Reported here is an inexpensive route to 2,6-dibromo-4-(hexoxymethyl)pyridine from citrazinic acid with an overall yield of 44% and its efficient conversion (60%) to 6,6'-dibromo-4,4'-di(hexoxymethyl)-2,2'-bipyridine via oxidative coupling.
