Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cavitation bioeffects.

Eitan Kimmel1

  • 1Biomedical Engineering Department, Technion, Haifa, Israel. eitan@bm.technion.ac.il

Critical Reviews in Biomedical Engineering
|June 6, 2006
PubMed
Summary
This summary is machine-generated.

Acoustic cavitation, the oscillation and collapse of gas bubbles in ultrasound, causes bioeffects in tissues. This review covers mechanisms and therapeutic applications, from cell damage to drug delivery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel ischemia reperfusion injury hereditary tissue model for pressure ulcers progression.

Biomechanics and modeling in mechanobiology·2019
Same author

The beginning of a new era: treatment of erectile dysfunction by use of physical energies as an alternative to pharmaceuticals.

International journal of impotence research·2019
Same author

Correspondence: Revisiting the theoretical cell membrane thermal capacitance response.

Nature communications·2017
Same author

Cell-Type-Selective Effects of Intramembrane Cavitation as a Unifying Theoretical Framework for Ultrasonic Neuromodulation.

eNeuro·2016
Same author

Extracorporeal acute cardiac pacing by high intensity focused ultrasound.

Progress in biophysics and molecular biology·2014
Same author

Low intensity ultrasound perturbs cytoskeleton dynamics.

Soft matter·2013

Area of Science:

  • Acoustic cavitation and bioeffects
  • Ultrasound physics and biological interactions

Background:

  • Acoustic cavitation involves gas bubble dynamics in ultrasonic fields.
  • Bioeffects occur in vivo and in vitro from low- and high-power ultrasound exposure.

Purpose of the Study:

  • To review cavitation bioeffects and their underlying mechanisms.
  • To discuss therapeutic applications of acoustic cavitation.

Main Methods:

  • Review of theoretical studies, simulations, and experimental data.
  • Analysis of bioeffects induced by gas bubble collapse in biological tissues.

Main Results:

  • Bioeffects range from severe cell necrosis to increased cell membrane permeability.
  • Gas bubble location near endothelium or red blood cells is crucial for bioeffects.

Related Experiment Videos

Conclusions:

  • Acoustic cavitation presents diverse bioeffects with significant therapeutic potential.
  • Applications include stone pulverization, tissue ablation, gene transfection, and transdermal delivery, with growing use of microbubbles.