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Leg ulcer recurrence and its risk factors: a duplex ultrasound study before and after vein surgery
M B Magnusson1, O Nelzén, R Volkmann
1Department of Clinical Physiology, Cardiovascular Institute, Göteborg, Sweden. marie.magnusson@vgregion.se
Insights
Varicose vein surgery can reduce chronic leg ulcer recurrence. Eliminating incompetent veins lowers risk, while residual reflux increases it, highlighting the importance of postoperative assessment for identifying high-risk patients.
Area of Science:
- Vascular Surgery
- Dermatology
- Phlebology
Background:
- Chronic leg ulcers often stem from venous insufficiency.
- Recurrence is a significant challenge in managing these ulcers.
- Varicose vein surgery is a treatment option, but risk factors for recurrence need identification.
Purpose of the Study:
- To identify risk factors for chronic leg ulcer recurrence after varicose vein surgery.
- To assess the effectiveness of postoperative investigations in predicting recurrence.
Main Methods:
- Retrospective follow-up study of 62 patients (CEAP C(5)-C(6), E(P)) undergoing varicose vein surgery.
- Pre- and postoperative colour duplex ultrasound (CDU) and ambulatory venous pressure (AVP) measurements.
- Median follow-up of 5.5 years.
Main Results:
- The 5-year ulcer recurrence rate was 19%.
- Lower recurrence risk was observed in legs without residual varices or reflux.
- Key risk factors identified included time to surgery, postoperative venous axial reflux, and AVP.
Conclusions:
- A long ulcer history is a risk factor for recurrence.
- Complete elimination of incompetent veins reduces recurrence risk; residual reflux increases it.
- Postoperative CDU effectively identifies patients at risk for ulcer recurrence.
Objectives:
Assessment of risk factors for ulcer recurrence in chronic leg ulcer patients treated by varicose vein surgery.
Design:
Retrospective follow-up study.
Materials:
62 patients, 43 women and 19 men (Median=56.5 years, range 24-77) with the CEAP classifications of C(5)-C(6) and E(P) (primary venous insufficiency).
Methods:
Patients underwent colour duplex ultrasound (CDU) investigation before varicose vein surgery. Post-operatively CDU, ambulatory venous pressure (AVP) and an interview were performed. The median clinical follow-up was 5.5 years (range 2-11 years).
Results:
The estimated 5-year ulcer recurrence rate was 19% in all patients. The risk of ulcer recurrence was significantly lower (p<0.05) in legs without residual varices or recurrence. The five year risk of ulcer recurrence depended on the time interval between ulcer appearance and the surgical intervention (index operation), post-operative venous axial reflux and AVP (mmHg). More than 50% of the patients had a calculated probability of ulcer recurrence of less than 3%, but 13% had a probability of more than 23% based on our analysis.
Conclusions:
A long history of venous ulcer is a pre- and post-operative risk factor for recurrent ulceration. Total elimination of incompetent superficial and perforator veins lowers the risk of ulcer recurrence, whereas residual axial reflux increases the risk. Postoperative CDU is effective in identifying patients at risk of ulcer recurrence.
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