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Intentional self-poisoning with glyphosate-containing herbicides
D B Menkes1, W A Temple, I R Edwards
1Department of Psychological Medicine, University of Otago Medical School, Dunedin, New Zealand.
Human & Experimental Toxicology
|March 1, 1991
Summary
Self-poisoning with Roundup herbicide can cause severe gastrointestinal issues and kidney failure, with one fatality reported. Management strategies and surfactant toxicity are crucial considerations in these serious cases.
Area of Science:
- Toxicology
- Clinical Medicine
- Environmental Health
Background:
- Self-poisoning incidents involving herbicides present significant public health challenges.
- Understanding the toxic effects of specific herbicides like Roundup is critical for effective medical intervention.
Observation:
- Four cases of self-poisoning with Roundup herbicide were documented.
- One case resulted in a fatality, while another survivor required extensive hospitalization.
- Detailed clinical and laboratory data were collected from the survivor.
Findings:
- Severe self-poisoning with Roundup is strongly linked to substantial gastrointestinal fluid loss.
- Renal failure is a significant complication observed in these cases.
- The role of surfactant toxicity in Roundup poisoning requires further investigation.
Implications:
- Effective management protocols for severe herbicide poisoning are essential.
- Clinical awareness of potential complications like renal failure is paramount.
- Further research into the specific toxic mechanisms, including surfactant effects, is warranted.