Multisectored interstitial ultrasound applicators for dynamic angular control of thermal therapy
Adam M Kinsey1, Chris J Diederich, P Daniel Tyreus
1Thermal Therapy Research Group, Department of Radiation Oncology, University of California, San Francisco, California 94115-1708, USA.
Medical Physics
|June 7, 2006
Summary
New multisectored interstitial ultrasound devices offer precise angular control for thermal ablation and hyperthermia treatments, eliminating the need for mechanical adjustments. These devices enable dynamic, non-invasive manipulation of heating patterns for improved therapeutic outcomes.
Area of Science:
- Medical Physics
- Biomedical Engineering
- Oncology
Background:
- Current interstitial heating technologies for thermal ablation and hyperthermia have limited angular control.
- Existing methods often rely on fixed power deposition patterns or mechanical device manipulation.
Purpose of the Study:
- To investigate the potential of multisectored tubular interstitial ultrasound devices for dynamic angular heating control.
- To assess the feasibility of achieving controlled angular heating distribution without device manipulation.
Main Methods:
- Development and incorporation of multisectored tubular transducers with independent sector power control into interstitial ultrasound applicators.
- Evaluation through acoustic beam measurements, ex vivo thermal lesion analysis, biothermal simulations, and in vivo MR temperature imaging.
Main Results:
- Multisectored devices demonstrated dynamic angular control of heating patterns without mechanical manipulation.
- Ex vivo lesions showed contiguous coagulation zones, and simulations confirmed angular control via variable power and duration.
- In vivo MR thermal imaging validated angular controllability and effective heating penetration.
Conclusions:
- Multisectored interstitial ultrasound applicators provide significant dynamic angular control of heating patterns.
- These devices maintain effective heat penetration, offering an advancement over current technologies for thermal therapies.
