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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Primitive mucinous adenocarcinoma of the bladder. A case report
Stefano Lauretti1, Augusto Mosca, Valeria D'Alfonso
1Unit of Urology, CTO Andrea Alesini Memorial Hospital, Rome. lauretti.stefano@aslrmc.it
Abstract:
Primary mucing-producing adenocarcinoma of the bladder is a rare, highly malignant tumor. It is classified as the third most frequent histologic type of bladder carcinoma characterized by a poor response to radiotherapy and/or chemotherapy. Only surgery seems to offer the best approach to this unusual cancer The authors report the pathological findings and the clinical course of a 45-years old man with a primary mucin-secreting adenocarcinoma of the bladder. At recovery for recurrent macrohematuria, the patient presented a 15 centimeters, squat endovesical neoformation with a large base and heavy, daily bleeding. This symptom was present during several years but the patient always refused any urological consultation due to personal refusal to be cured. On the fifteenth day the patient died for cardio-respiratory arrest.
