Hunter syndrome (MPS II-B): a report of bilateral vitreous floaters and maculopathy

To describe bilateral vitreous opacities and maculopathy in a child with Hunter syndrome.

A case involving fundus examination, photography, and optical coherence tomography. Medline and Embase searches found no reference to vitreous or macular abnormalities in Hunter syndrome.

A two-year-old boy with Hunter syndrome was found to have asymmetric, bilateral, free-floating vitreous opacities that remained stable over six years. Amblyopia and exotropia improved with occlusion therapy and spectacle correction. Visual acuity decreased when bilateral maculopathy supervened.

Screening for vitreous abnormalities and maculopathy may be important in diagnosing, treating, and explaining visual loss in Hunter syndrome.