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Cigarette smoking during pregnancy and hyperactive-distractible preschooler's: a follow-up study
Karen Markussen Linnet1, Carsten Obel, Else Bonde
1Perinatal Epidemiology Research Unit, Department of Obstetrics and Paediatrics, Aarhus University Hospital, Skejby Sygehus, Denmark. kmlinnet@ki.au.dk
Insights
Maternal smoking during pregnancy is linked to increased hyperactivity and distractibility in preschool children. This study found a 60% increased risk for children exposed to 10 or more cigarettes daily in utero.
Area of Science:
- Developmental Psychology
- Prenatal Health
- Pediatric Behavioral Science
Background:
- Intrauterine exposure to environmental factors can impact child development.
- Maternal smoking is a known risk factor for various adverse pregnancy outcomes.
Purpose of the Study:
- To investigate the association between prenatal tobacco smoke exposure and behavioral disorders in preschoolers.
- To examine symptoms of inattention, hyperactivity, impulsivity, and aggressive or anxious behaviors.
Main Methods:
- A follow-up study of 1355 singletons born to Danish mothers.
- Maternal smoking data collected via questionnaires during pregnancy.
- Child behavior assessed at approximately 3.5 years using the Preschool Behaviour Questionnaire.
Main Results:
- Children of mothers smoking 10+ cigarettes daily had a 60% increased risk of hyperactivity/distractibility (OR 1.6).
- Results remained significant after adjusting for lifestyle, socioeconomic, perinatal, and parental psychiatric factors (OR 1.7).
- No significant association found between maternal smoking and hostile-aggressive or anxious-fearful behaviors.
Conclusions:
- Prenatal exposure to tobacco smoke is associated with hyperactive-distractible behavior in preschool children.
- The findings highlight a specific behavioral risk linked to maternal smoking during gestation.
Aim:
To study the association between intrauterine exposure to tobacco smoke and behavioural disorders in preschool children, primarily symptoms of inattention, hyperactivity and impulsivity but also hostile-aggressive and anxious-fearful symptoms.
Methods:
We conducted a follow-up study in 1355 singletons born to Danish-speaking mothers. Information on smoking habits during pregnancy and other lifestyle factors was obtained from self-administered questionnaires filled in during second and third trimester. Approximately 3.5 years later, the parents provided information on their child's behaviour using the self-administered Preschool Behaviour Questionnaire. The children were categorized into three not mutually exclusive behaviour groups: hyperactive - distractible (13.6%), hostile-aggressive (4.6%), and anxious-fearful (6.4%) children.
Results:
Compared with children of non-smokers, children born to women who smoked 10 or more cigarettes per day had a 60% increased risk of hyperactivity and distractibility perceived by the parents (OR 1.6; 95% CI 1.0-2.3; P < 0.05). The results were adjusted for maternal lifestyle factors and socioeconomic characteristics. Additional adjustment for perinatal factors and parental psychiatric hospitalization did not change the results substantially (OR 1.7; 95% CI 1.1-2.6). We found no statistically significant association between maternal smoking in pregnancy and hostile-aggressive and anxious-fearful behaviour in the offspring.
Conclusion:
Exposure to tobacco smoke in utero was associated with hyperactive-distractible behaviour in preschool children.
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