An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which
1Research School of Chemistry, Australian National University, Canberra, Australia. pdc@rsc.anu.edu.au
Abstract:
X-ray diffraction has been used to produce and refine a model of the extracellular domains of the beta common cytokine receptor. A minor improvement in resolution has resulted in improved electron-density maps, which have given a clearer indication of the position and stabilization of the key residues Tyr15, Phe79, Tyr347, His349, Ile350 and Tyr403 in the elbow region between domain 1 and domain 4 of the dimer-related molecule.
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