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The role of global risk assessment in hypertension therapy

S A Grover1, Brenda Hemmelgarn, Lawrence Joseph

  • 1Centre for the Analysis of Cost-Effective Care, Division of Clinical Epidemiology, The Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec, Canada. steven.grover@mcgill.ca

The Canadian Journal of Cardiology
|June 7, 2006
PubMed

Insights

Cardiovascular disease risk assessment tools are needed for Canadians. This review identifies and evaluates global risk models, proposing a framework to help clinicians select the best tool for patient care.

Area of Science:

  • Cardiology
  • Preventive Medicine
  • Biostatistics

Background:

  • Cardiovascular disease (CVD) risk assessment is crucial for preventive therapy.
  • Guidelines recommend targeting high-risk individuals for treatment.
  • Accurate CVD risk estimation requires considering multiple factors like age, lipids, and smoking.

Purpose of the Study:

  • To identify cardiovascular risk assessment tools suitable for Canadians.
  • To evaluate the accuracy of existing models using Canadian data.
  • To propose a framework for selecting appropriate risk tools.

Main Methods:

  • Systematic review of global cardiovascular risk models.
  • Evaluation of Framingham and Cardiovascular Life Expectancy models using a Canadian cohort.
  • Development of a framework for tool selection.

Main Results:

  • Several international risk models (Framingham, UKPDS, SCORE, Cardiovascular Life Expectancy) were identified as potentially applicable to Canadians.
  • The Framingham and Cardiovascular Life Expectancy models showed varying accuracy when tested with Canadian data.
  • A framework was proposed to guide healthcare professionals in choosing the most appropriate global risk tool.

Conclusions:

  • No Canadian-specific global risk assessment model currently exists.
  • International models can be used for Canadian risk assessment, but their accuracy needs consideration.
  • A structured approach is needed to help clinicians select the best cardiovascular risk tool for their patients.

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