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Updated: Aug 8, 2026
10:19
A Murine Model of Group B Streptococcus Vaginal Colonization
Published on: November 16, 2016
[Streptococcus agalactiae in nonpregnant adults]
Adnène Toumi1, Asma Ferjani, Hajer Ben Abdallah
1Laboratoire de Microbiologie, CHU Farhat Hached Sousse, Tunisie.
La Tunisie Medicale
|June 8, 2006
Summary
Group B Streptococcus (GBS) infections are rising in nonpregnant adults. This study found GBS strains in Tunisia remain susceptible to key antibiotics like penicillin, though erythromycin resistance is noted.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Bacteriology
Context:
- Increasing incidence of Streptococcus agalactiae (Group B Streptococcus, GBS) infections in nonpregnant adults.
- Need to understand local GBS pathogenic capacity and antibiotic susceptibility patterns.
- Study conducted at Farhat Hached hospital, Sousse, Tunisia.
Purpose:
- To investigate the pathogenic capacity and antibiotic susceptibility of GBS strains isolated from nonpregnant adults.
- To identify common sources of GBS infections in this demographic.
- To assess resistance patterns to commonly used antibiotics.
Summary:
- Sixty GBS strains were isolated from January 2003 to June 2004, primarily from urinary tract (52%) and skin (36.2%) infections.
- Women constituted 68% of cases, and hospitalized patients often had underlying conditions, predominantly diabetes mellitus (80%).
- All GBS isolates were susceptible to amoxicillin, penicillin G, vancomycin, and pristinamycin, while 64% were susceptible to erythromycin.
Impact:
- Provides crucial data on GBS epidemiology and antibiotic resistance in a Tunisian general hospital setting.
- Highlights the continued effectiveness of penicillin and amoxicillin against GBS in this population.
- Informs clinical management and public health strategies for GBS infections in nonpregnant adults.
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