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A Mouse Model of Hemorrhagic Transformation Induced by Acute Hyperglycemia Combined with Transient Focal Ischemia
Published on: November 15, 2024
Hyperglycemia in acute cerebral infarction
1Division of Neurology, Department of Medicine, Ratchaburi Hospital, Thailand.
Objective:
Report the results of hyperglycemia in the patients with acute cerebral infarction.
Material And Method:
A retrospective review of 231 patients who presented with the syndrome of acute cerebral infarction at Ratchaburi Hospital from January 1, 2000 to December 31, 2004. Patients data, diagnosis, blood glucose, and underlying disease were collected from medical records (n = 231).
Results:
Hyperglycemia is defined as the blood glucose level of more than 140 mg/dl. Odd ratio for 1 year mortality was calculated using multivariable Cox regression models. Admission hyperglycemia was present in 43.7 % of patients with acute cerebral infarction. 61% of these patients received oral hypoglycemic drugs during their hospital admission. Hyperglycemic patients had a longer hospital stay than normoglycemics (6.91 vs 4.60, p < 0.001) and increased risk for death at 1 year (odd ratio = 1.004, p < 0.01).
Conclusion:
Hyperglycemia can predict mortality of acute cerebral infarction.
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