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Myasthenia gravis accompanied with hypokalemic periodic paralysis
K Sawanyawisuth1, S Tiamkao, T Pratipanawatr
1Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
Abstract:
Myasthenia gravis and hypokalemic periodic paralysis are commonly related with hyperthyroidism but rarely occur together. Here, the authors reported a case of hypokalemic periodic paralysis in a Northeastern Thai woman accompanied with myasthenia gravis. She had motor weakness despite a normal level of serum potassium. Prostigmine test was positive. She dramatically improved after pyridostigmine treatment. Autoantibodies to nicotinic AchR-Ab and dihydropyridine receptor or L-type voltage gated calcium channel were postulated to explain these associated diseases.
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