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Medicines for Malaria Venture: sustaining antimalarial drug development
Ian Bathurst1, Chris Hentschel
1Medicines for Malaria Venture (MMV), International Center Cointrin (ICC) Building, 20 rte de Pré-Bois, 1215 Geneva 15, Switzerland. bathursti@mmv.org
Abstract:
The Medicines for Malaria Venture (MMV) is committed to discovering, developing and delivering new drugs for malaria. Founded in 1999 as a nonprofit organization bringing private sector management methods to bear on a global public health problem, MMV is today recognized as a leader among the public-private partnerships working on diseases for the developing world. Together with its many partners, MMV manages the world's largest malaria research and development portfolio, covering the innovation spectrum from basic drug discovery to late-stage development.
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The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...