Related Experiment Video

Updated: Aug 8, 2026

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
10:16

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines

Published on: October 8, 2015

Sequencing analysis of BRAF mutations in human cancers

Richard Wooster1, Andrew P Futreal, Michael R Stratton

  • 1Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.

Methods in Enzymology
|June 8, 2006
PubMed
Summary

Cancer develops from gene mutations. The RAS-RAF-MEK-ERK-MAP kinase pathway is key, with BRAF gene mutations, particularly V600E, common in many human cancers.

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