Related Experiment Video
Updated: Aug 8, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
Aortic valve replacement in true severe aortic stenosis with low gradient and low ejection fraction
Ibrahim Ozsöyler1, Banu Lafci, Bilgin Emrecan
1Department of Cardiovascular Surgery, Atatürk Training and Research Hospital, Izmir, Turkey.
Aortic valve replacement improves function and ejection fraction in patients with severe aortic stenosis and low left ventricular ejection fraction. This surgery offers acceptable mortality and significantly enhanced functional status for these high-risk patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Echocardiography
Background:
- Severe aortic stenosis with reduced left ventricular ejection fraction and low gradient presents uncertain surgical outcomes.
- Aortic valve replacement (AVR) is a critical intervention for these complex cases.
Purpose of the Study:
- To evaluate the outcomes of AVR in 27 patients with severe aortic stenosis, left ventricular ejection fraction (LVEF) ≤30%, and mean transvalvular gradient <30 mmHg.
- To assess the impact of recruitable myocardium on functional capacity and LVEF post-AVR.
Main Methods:
- Retrospective analysis of 27 patients undergoing AVR between 2000-2005.
- Patients stratified into two groups based on dobutamine echocardiography: recruitable myocardium (Group 1, n=16) vs. non-recruitable (Group 2, n=11).
- Exclusion criteria included coronary artery disease and concomitant valvular procedures.
Main Results:
- All patients in Group 1 showed significant improvement in functional capacity (P=.001) and LVEF (P<.001) post-AVR.
- Group 2 patients also demonstrated significant functional improvement (P=.001), though LVEF changes were not statistically significant (P=.096).
- Functional capacity improvement was significantly greater in Group 1 (P=.039).
Conclusions:
- Aortic valve replacement is associated with acceptable mortality rates in patients with severe aortic stenosis and left ventricular dysfunction.
- AVR leads to significant improvements in functional capacity and left ventricular ejection fraction in this high-risk population.
- Identifying recruitable myocardium may predict greater functional recovery after AVR.
More Related Videos
Related Concept Videos
Aortic Regurgitation III: Medical Management
Mitral Stenosis III: Medical Management
Aortic Regurgitation I: Introduction
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation IV: Nursing Management
Mitral Stenosis I: Introduction

