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[Hantaan virus infection in Twente]
J G Jordans1, J Groen, J Clement
1Medisch Spectrum Twente, Ziekenhuis Enschede, afd. Inwendige Geneeskunde.
Nederlands Tijdschrift Voor Geneeskunde
|May 4, 1991
Summary
Hantavirus infection, a cause of acute renal failure, has been underdiagnosed in the Twente area. The virus was detected in both patients and red bank voles, indicating a persistent presence.
Area of Science:
- Infectious Diseases
- Nephrology
- Environmental Health
Context:
- A retrospective study was conducted in the Twente area, examining patients hospitalized between 1970 and 1989.
- The study focused on cases of acute renal failure attributed to acute interstitial nephritis of unknown etiology.
Purpose:
- To investigate the potential underdiagnosis of Hantavirus infection as a cause of acute renal failure.
- To determine the prevalence of Hantavirus in wild rodents, specifically red bank voles, within the study region.
Summary:
- Anti-Hantavirus antibodies were detected in 5 out of 10 investigated patients with acute renal failure, suggesting local acquisition of the infection.
- Hantaviral antigen and specific antibodies were identified in 4 out of 10 trapped red bank voles.
Impact:
- The findings indicate that Hantavirus infections have been occurring and underdiagnosed in the Twente area for an extended period.
- This research highlights the importance of considering Hantavirus in the differential diagnosis of acute renal failure in endemic regions.