Related Experiment Video
Updated: Aug 8, 2026

Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
Published on: June 20, 2018
[Nephrocalcinosis due to renal tubular acidosis in two brothers]
Naoki Segawa1, Satoshi Kiyama, Haruhito Azuma
1The Departments of Urology, Osaka Medical College.
Abstract:
A 25-year-old man was admitted to our hospital because of left lumbago. An abdominal X-ray film demonstrated multiple calculi in the medullary positions of both kidneys and an impacted calculus in the left ureter. He was diagnosed with bilateral nephrocalcinosis and nerve deafness due to distal renal tubular acidosis (RTA) in childhood and was treated with alkali agents for several years. Extracorporeal shock wave lithotripsy was performed successfully against the left ureteral calculus. His older brother had also been diagnosed with RTA and nephrocalcinosis at the age of 2 years and 6 months. Nephrocalcinosis due to RTA associated with nerve deafness in brothers is rarely reported.
Related Concept Videos
Nephrons
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Urinary Tract Calculi I: Introduction
Acute Kidney Injury II: Pathophysiology
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Nephrotic Syndrome II : Assessment and Medical Management
