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Updated: Aug 8, 2026

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model
Published on: August 4, 2012
[Blood oxygen-transporting function during different anesthesiological provision procedures in the surgery of the
Abstract:
A comparative analysis of blood oxygen-transportingfunction (BOTF) under 6 types of combined general anesthesia (low-flow inhalational anesthesia in combination with a narcotic analgesic or with continuous graded epidural infusion (CGEI) of local anesthetics) during high-traumatic and prolonged operations on the hepatopancreaoduodenal area has revealed no significant abnormalities of tissue oxygen transport and metabolism. At the same time when a procedure of anesthesia is chosen for this category of patients, preference should be given to a combination of CGEI and low-flow inhalational anesthesia with isoflurane in nitrous-oxide mixture, which provides a minimum drug load, optimal conditionsfor cardiovascular performance, and stability of BOTF parameters even in baseline endotoxicosis.
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